Clinical Imaging


The Department of Nuclear Medicine & PET center of the Ghent University Hospital provides the diagnostic and therapeutic services of nuclear medicine and molecular imaging to patients most often intramural, sometimes regional and occasionally national and international. It has a long history of using virtually all kind of isotopes and tracers. On the department, some 30 people are daily occupied at the patient-related conventional activities of nuclear medicine, including therapy, SPECT, PET and cyclotron activities. From here, a lot of isotopes additionally find their way to research projects around the campus and the university. The department has collaborations with several national and international research groups as well as contract research with industry. Main focus areas are image-guided therapy and dosimetry, development of new SPECT and PET tracers, clinical implementation of innovative imaging systems and value-based health care economics.

Table of currently used techniques in the clinic


PET/CT imaging: Dynamic imaging, Organ imaging, Whole-body imaging

Clinical Application Tracer

Bone scintigraphy

99mTc-MDP

Salivary gland scintigraphy

99mTc -pertechnetate

Thyroid scintigraphy

99mTc -pertechnetate; 123I; 131I

Parathyroid scintigraphy

99mTc -sestamibi

Esophageal reflux (“milk”)

99mTc -MDP

Stomach emptying

99mTc -MDP

Gastro-intestinal bleeding

99mTc -PYP

Meckel’s diverticulum

99mTc -pertechnetate

Gastric banding leakage

99mTc -pertechnetate

Hepato-biliary scintigraphy

99mTc -HIDA

Lung perfusion scintigraphy

99mTc -MAA

Lung ventilation scintigraphy

99mTc -DTPA

Cardiovascular shunting

99mTc -MAA

Cardiac ejection fraction

99mTc -HSA

Lympho-scintigraphy

99mTc -nanocolloid

Sentinel node detection

99mTc -nanocolloid

Leucocyte scintgraphy

99mTc -HMPAO

Bone marrow scintigraphy

99mTc -nanocolloid

Red blood cell mass

99mTc -PYP

Renal cortical imaging

99mTc -DSMA

Renal dynamic imaging

99mTc -MAG3

Glomerular filtration rate

51Cr-EDTA

Brain perfusion scintigraphy

99mTc ECD

Brain dopamine scintigraphy

123I-FPCIT

CSF fluid circulation scintigraphy (RISA)

111In-DTPA

Neuro-endocrine tumors

123I-MIBG

PET/CT imaging: Dynamic imaging, Organ imaging, Whole-body imaging

Clinical Application

Tracer

Oncology; Myocardial viability; Infection and Inflammation; Neurodegenerative disease; Epilepsia

18F-FDG

Oncology

18F-choline

Neuro-oncology

18F-FET

Parkinsonism

11C-raclopride

Radionuclide therapy

 

Clinical Application

Tracer

Thyroid disease benign and malignant

131I

Bone metastases

159Sm-EDTMP (Samarium)

Bone metastases

223Ra (Xofigo)

Radiosynovectomy

90Y; 186Re

Neuro-endocrine tumors

131I-MIBG

Brain tumors

90Y

Liver tumors

90Y-microspheres (Therasphere, Sirtex)


Abbreviations: Tc=Technetium; I=Iodine; In=Indium; F=Fluor; C=Carbon,; Cr=Chromium; Sm=Samarium; Y=Yttrium; Re=Rhenium, Ra=Radium.